What are the advantages of peptides

What are the advantages of peptides

Peptides are bioactive substances that have multiple cellular functions in living organisms. Peptides are compounds formed by peptide bonds of alpha amino acids and are intermediate products of protein hydrolysis. Usually, compounds dehydrated and contracted by three or more amino acid molecules can become peptides.

With the growing maturity of biotechnology and peptide synthesis technology, more and more peptide drugs have been developed and applied in clinical practice. Peptide drugs are widely used in the prevention, diagnosis and treatment of cancer, hepatitis, diabetes, AIDS and other diseases due to their wide range of indications, high safety and significant therapeutic effects.

Due to its own characteristics, the time from clinical trials to FDA approval is much shorter than that of small molecule drugs, with an average time of about 10 years. The likelihood of peptide drugs passing clinical trials is twice that of small molecule compounds. The advantages of peptides have shown unique advantages and clinical application value in drug development.

Peptide drugs are easily broken down rapidly in the body and require low-temperature storage. However, the stability of peptides can be improved by modifying or forming stable complexes with other materials. Compared with macromolecular proteins and antibodies, peptides are stable at room temperature, require less use, and have higher unit activity.

Peptides are easily separated from impurities or by-products and have high purity. It is difficult to guarantee the quality, purity, and yield of proteins. Recombinant proteins cannot be introduced into non natural amino acids, nor can they undergo amination at the end of the protein. Meanwhile, the production cycle is long and the cost is high.